The Second Maryland Regiment, Potomac Home Brigade Infantry lost 1 officer and 9 enlisted men killed or mortally wounded and 84 enlisted men to disease during the Civil War.

August 27-
October 31
Organized at Cumberland, Md. for duty on Baltimore & Ohio Railroad, at Patterson Creek and Romney, W. Va. All of the regiment was recruited from Allegheny County except Company F from Hancock County and Company D from Piedmont, Virginia. It was attached to the Railroad District, West Virginia.
August 23 Skirmish at Springfield, W. Va.
August 26 Skirmish at Blue House
October 26 Skirmishes at South Branch Bridge, Mill Creek Mills, Romney and Springfield
January 4 Skirmish at Great Cacapon Bridge
February Attached to District of Cumberland, Mountain Department. Duty at Charlestown, New Creek and Cumberland guarding Baltimore & Ohio Railroad to the Ohio River
March Duty from Monocacy Bridge to the Ohio River
April Attached to Railroad District, Dept. of the Mountains
July Attached to Railroad District, 8th Army Corps, Middle Department
September 17 Action at Vance’s Ford, near Romney.
September Attached to Railroad Division, District of West Virginia, Dept. of the Ohio
January Attached to Cumberland, Md., Defenses Upper Potomac. 8th Army Corps, Middle Dept.

Company F under Captain George D. Summers was monuted as cavalry and attached to Cavalry, Martinsburg, W. Va.; 8th Army Corps. It would operate independently from the infantry until the end of the war.

March Attached to 5th Brigade, 1st Division, 8th Army Corps. Company F was attached to 3rd Brigade, 1st Division. 8th Army Corps
May 15 Charlestown. W. Va.
June Attached to Mulligan’s Brigade, Scammon’s Division, Army of West Virginia. Company F attached to 1st Brigade, Maryland Heights, Division West Virginia
June 14

Company F skirmished with part of Rodes’ Confederate Division

June 17 Point of Rocks (Company F)
October 7
Summit Point

Company F skirmished with Gilmor’s Battalion of Confederate Cavalry. Captain George D. Summer was killed leading a cavalry charge.

October 18 Charlestown, W. Va.
November 16 Burlington
December Attached to 2nd Brigade, 2nd Division West Virginia. Company F was attached to Cavalry, 1st Division West Virginia
December 16 Salem
December 19 Jackson River, near Covington
January 4 Ridgeville, Va.
January 8 Moorefield Junction
January 30 Medley
April Company F was attached to Reserve Division, Kelly’s Command, West Virginia
May 26-July 1 Hunter’s Raid on Lynchburg
June 17-18 Lynchburg
June 21 Salem
July 4 Salem Branch Bridge
July 6 Saint John’s Run
July 18 Snicker’s Gap
July 24 Kernstown, Winchester
July 25 Martinsburg
July 27 Back Creek Bridge
July 31 Hancock, Md.
August 2 Green Springs Run
August Guard duty in West Virginia
October Original members mustered out. Recruits and Veterans reorganized into a battalion of three companies.
March A new Company D was recruited for one year service
April Company F attached to 2nd Brigade, 1st Division West Virginia
May 29 Mustered out