The 5th Maryland Volunteer Infantry Regiment lost 1 officer and 63 enlisted men killed or mortally wounded and 6 officers and 91 enlisted men to disease during the Civil War. There are two monuments to the 5th Maryland at Antietam.

September Organized at Baltimore, Md. and attached to Dix’s Division, Baltimore, Md. Camp at LaFayette Square, Baltimore, Md.
March 11 Ordered to Fortress Monroe, Va.
March Duty at Fort Monroe
July At Suffolk, Va. Attached to Weber’s Brigade, Division at Suffolk, Va., 7th Army Corps, Dept. of Virginia
September 8-16 Moved to Washington, D. C., then to Antietam, Md. Attached to 3rd Brigade, 3rd Division, 2nd Army Corps, Army of the Potomac
September 16-17
Battle of Antietam

From the main regimental monument at Antietam:

Advanced to the knoll above the Bloody Lane, 300 feet in rear of this marker. Loss 43 killed, 123 wounded.

From the monument to Companies A & I, a short distance to the north:

This stone marks the extreme advance of Weber’s Brigade French’s Div. 2nd Army Corps. Can their glory ever fade.

September 22 Moved to Harper’s Ferry
October 16-17 Reconnaissance to Charleston
December Assigned to Point of Rocks Defenses, Upper Potomac, 8th Army Corps, Middle Department. At Point of Rocks and Maryland Heights protecting Baltimore & Ohio Railroad
March Attached to 2nd Brigade, 1st Division, 8th Army Corps
June 2 Moved to Winchester, Va.
June 13-15
Second Battle of Winchester

Most of the regiment was captured in the rout of Milroy’s force at Stephenson Depot.

June Those not captured at Winchester to Bloody Run, Pa., and Loudon, Pa.
July Duty in the Defenses of Baltimore, Middle Department, 8th Army Corps
January Assigned to the District of Delaware, Middle Department
June 4 Ordered to join Army in the field; assigned to 3rd Brigade, 2nd Division, 18th Army Corps, Army of the James
June 16 Siege operations against Petersburg and Richmond, Va.
July 30 Mine Explosion, Petersburg (Reserve)
August Duty in trenches before Petersburg assigned to 2nd Brigade, 1st Division, 18th Army Corps
September 28-30 Battle of Chaffin’s Farm, New Market Heights
October 27-28 Battle of Fair Oaks
November Duty in trenches before Richmond
December Assigned to 2nd Brigade, 3rd Division, 24th Army Corps
April 3 Occupation of Richmond
April 3-9 Pursuit of Lee to Appomattox Court House
April 9
Appomattox Court House

Surrender of Lee and his army.

May Duty in the Dept. of Virginia
July Assigned to 2nd Independent Brigade, 24th Army Corps
September 1 Mustered out at Fredericksburg, Va.