The 135th Pennsylvania Infantry lost 7 enlisted men to disease during the Civil War.

1862
August Organized at Harrisburg under Colonel James R. Porter for nine months service.
August 19 Moved to Washington, D.C. and attached to Military District of Washington, D.C. for Provost duty at Washington and Georgetown
1863
February Joined the Army of the Potomac and duty at Falmouth and Belle Plains, Va. attached to 3rd Division, 1st Army Corps
April 27-May 6 Chancellorsville Campaign
April 29-May 2. Operations at Pollock’s Mill Creek
April 29-30 Fitzhugh’s Crossing
May 2-5 Battle of Chancellorsville
May 24 Mustered out