The 165th Pennsylvania Infantry Regiment lost 1 enlisted man killed and 1 officer and 14 enlisted men to disease during the Civil War.

1862
November 25-December 5 Organized at Chambersburg and Gettysburg under Colonel Charles H. Buehler, Lt. Colonel Edward G. Fahnestock and Major Nash G. Camp
December 8-17 Moved to Washington, D. C, then to Newport News and Suffolk, Va.
December Duty at Suffolk attached to Foster’s Brigade, Division at Suffolk, 7th Corps, Dept. of Virginia
1863
January 8-10 Expedition toward Blackwater, Va.
January 30 Deserted House
April 4 Leesville
April 11-May 4 Siege of Suffolk. Attached to 2nd Brigade, 1st Division, 7th Corps, Dept. of Virginia.
April 12-13 Edenton, Providence Church and Somerton Roads
April 15 and 20 Somerton Road
April 24 Edenton Road

The regiment lost one killed, and one mortally and several lightly wounded.

May 12-26 Operations on Seaboard & Roanoke Railroad
May 15-16 Holland House, Carrsville
June 27-July 7 Dix’s Peninsula Campaign
July 1-7 Expedition from White House to South Anna River
July 4 South Anna Bridge
July 8 Moved to Washington, D.C.
July 28 Mustered out