The 133rd Pennsylvania Volunteer Infantry Regiment lost 4 officers and 40 enlisted men killed or mortally wounded and 33 enlisted men to disease during the Civil War.

1862
August Organized at Harrisburg under Colonel Franklin B. Speakman
August 19 Moved to Washington, D.C.
September 2 Moved to Rockville, Md. and attached to 2nd Brigade, 3rd Division, 5th Army Corps, Army of the Potomac.
September-October Duty at Sharpsburg, Md.
October 30-November 17 Moved to Falmouth, Va.
December 12-15
Battle of Fredericksburg
1863
January 20-24 Burnside’s 2nd Campaign, “Mud March”
February-April At Falmouth
April 27-May 6 Chancellorsville Campaign
May 1-5
Battle of Chancellorsville
May 26 Mustered out