|February-March||Organized over the winter under the command of Colonel Thomas Hardeman, Jr., Lieutenant Colonel Thomas J. Simmons
Company A – Gresham Rifles (Bibb County), Captain Matthew Roberts Rogers
|May||Transferred with Anderson’s Brigade to Virginia. Assigned to General J. R. Anderson’s Brigade, A.P. Hill’s Division, Army of Northern Virginia|
|May 15||Lieutenant Washington Leonidas Grice of the 6th Georgia Infantry Regiment was promoted to major of the 45th Georgia.|
Battle of Hanover Court House
|May 31-June 1||
Battle of Seven Pines
|June 1||Lieutenant Homer M. Key of Company C died of disease in Richmond.|
|June||Assigned to General J. R. Anderson’s-Thomas Brigade, General A. P. Hill’s Division, Longstreet’s Command, Army of Northern Virginia|
|June 25-July 1||Seven Days Battles|
Battle of Mechanicsville
Battle of Gaines’ Mill
Lieutenant Colonel Simmons and Captain Wallace of Company E were wounded. Captain William M. Davis of Company G was wounded, losing his leg to amputation and resulting in permanent disability. Lieutenant Harrison C. Barron of Company F was killed and Lieutenant James A. Woodall of Company F was mortally wounded, dying on June 30.
Battle of Frazer’s Farm
Lieutenant Milton Cleveland of company B was killed. Captain Aurelius W. Gibson of Company K and Lieutenants John Hall and Cicero Dickerson of Company I were wounded.
Battle of Malvern Hill
|July||Assigned to General Thomas’ Brigade, A. P. Hill’s Division, Jackson’s Command, Army of Northern Virginia|
|July 20||Lieutenant William Cobb died of disease at his home in Georgia.|
|July 25||Captain Bonner of Company F resigned due to disability.|
Battle of Cedar Mountain
Captain Wallace of Company E was wounded in the neck, arm and shoulder and Lieutenant William W. Huff of Company E was wounded. Lieutenant Tomlinson F. Newall of Company G was wounded and Lieutenant Robertson B. Brown of Company H was mortally wounded, dying the next day.
|August 11||Lieutenant John Green Brown was elected captain of Company H.|
|August 23||Lieutenant John T. Hardeman was elected captain of Company F.|
The regiment lost 7 men killed and 35 wounded. Captain Joseph H. White of Company D was mortally wounded on August 30 and would die on September 6.
|August 23||Lieutenant Charles N. Rountree was elected captain of Company G.|
|September 10||Lieutenant Jesse Mays was elected captain of Company D.|
The brigade was left at Harpers Ferry to finish the work of paroling Federal prisoners and securing captured supplies while the rest of A.P. Hill’s Division made its legendary forced march to Sharpsburg that saved Lee’s army.
|October 13||Colonel Hardeman resigned. Lieutenant Colonel Simmons was elected colonel, Major Grice was elected lieutenant colonel, Captain Matthew Roberts Rogers of Company A was elected major and Lieutenant John M. Pickett was elected captain of Company A.|
|October 28||Captain Brown of Company H resigned.|
|December 5||Captain DuPree of Company I resigned to become Post Surgeon at Griffin, Georgia. Lieutenant John I. Hall was elected captain of Company I.|
The regiment lost 5 men killed and 43 wounded. Lieutenant William R. McCrary of Company K was killed.
|December 23||Captain Jesse Mays of Company D resigned.|
|January 2||Captain John W. Dexler of Company B resigned. Lieutenant William L. Montgomery was elected captain of Company B.|
|January 5||Captain John M. Pickett of Company A resigned due to advanced age and defective eyesight. Lieuteant William H. Shaw was elected captain of Company A.|
|January 12||Lieutenant William H. Holmes died of pneumonia in General Hospital #9 in Richmond, Virginia.|
|February 13||Lieutenant Chesley M. Attaway of Company G resigned due to disability.|
|February 17||Lieutenant Thomas J. Slater of Company K died of smallpox.|
The regiment lost 35 casualties of the 350 men engaged. Captain William H. Shaw of Company A was killed.
|May 2-3||Captain Lieutenant Thomas D. Kinder was elected captain of Company A. Lieutenant John H. Baskin was elected captain of Company C.|
|May 6||Major Rogers resigned. Captain James W. Carter of Company C was promoted to major.|
|June 1||The regiment was assigned to Thomas’ Brigade of Pender’s Division in the newly-created Third Corps|
|June 22||Lieutenant Issac N. McCrary of Company G resigned due to disability.|
The regiment was commanded by Colonel Thomas J. Simmons. It lost 5 men killed, 32 wounded and 8 missing of the approximately 300 men engaged. Lieutenant Thomas B. Thompkins of Company B was mortally wounded on July 2. Lieutenant Christopher C. McGough was killed on July 2. Lieutenant Tomlinson F. Newall of Company G was wounded, losing his foot to amputation, and Lieutenant Cicero Dickerson of Company I was wounded.
From the monument to Thomas’ Brigade on the Gettysburg battlefield:
July 1. In reserve north of Chambersburg Pike on left of the Division. At sunset moved to position in McMillan’s Woods.
July 2. On duty in support of artillery. At 10 P. M. advancing took position in Long Lane with left flank in touch with McGowan’s Brigade and the right near the Bliss House and Barn.
July 3. Engaged most of the day in severe skirmishing and exposed to a heavy fire of artillery. After dark retired to this Ridge.
Battle of Williamsport
|July 31||Captain Charles Rountree of Company H resigned due to disability.|
|August 13||Major General Cadmus Wilcox took over the division from Brigadier General Lane, who had been temporary commander since Gettysburg.|
|October 30||Captain John Hall resigned. Lieutenant Jesse M. Carter was elected captain of Company I.|
|November-December||Mine Run Campaign|
|February 26||Captain Kinder of Company A was captured at Romney, Virginia.|
|March 10||Captain James W. Carter of Company C was elected major. William L. Montgomery of Company B resigned due to disability.|
|March 17||Lieutenant Colonel Grice resigned. Major Carter was promoted to lieutenant colonel, Captain Wallace of Company E was elected major, and Lieutenant William W. Huff was elected major of Company E.|
|April 10||Lieutenant Cicero Dickerson of Company I retired to the Invalid Corps.|
Captain Charles Augustus Conn of Company G was wounded. Lieutenant Anderson Riddle was wounded on May 5 and permanently disabled. Lieutenant George W. Johnston of company H was wounded in the hip and furloughed due to disability.
Battle of the North Anna
Captain John H. Baskin of Company C was killed on May 23 at Jericho Ford.
Captain Huff of Company E was wounded on June 3.
|June 15||Adjutant George F. Cherry was elected captain of Company A.|
|June 18||Crossed to south side of James River.|
|June 19||Petersburg Siege Begins|
Battle of Weldon Railroad
Lieutenant Colonel Carter was killed. Major Wallace was promoted to lieutenant colonel, and Captain Conn of Company G was elected major. Lieutenant Tomlinson Newall was elected Captain of Company G although he was at home, disabled from is wound.
|December 2||Lieutenant Colonel Wallace retired to Invalid Corps. Major Conn was promoted to lieutenant colonel and Captain Aurelius W. Gibson of Company K was elected major.|
|December 6||Captain Jesse M. Carter of Company I deserted and took the Oath of Allegiance to the United States in Baltimore.|
|January 23||Lieutenant Daniel S. Redding was elected captain of Company D.|
|February||Lieutenant Willam Rutherford was elected captain of Company K,|
Lieutenant Colonel Conn was killed and Major Aurelius W. Gibson was captured.
Fall of Petersburg
Captain Daniel S. Redding of Company D and Captain Huff of Company E were captured. Captain Hardeman of Company F was wounded, losing his thumb.
The regiment surrendered 8 officers and 85 enlisted men under the command of Colonel Thomas J. Simmons.