|March||Organized at Anderson, South Carolina.|
|April 14||Mustered into Confederate service under Colonel John B. Sloan, Lieutenant Colonel Charles S. Mattison and Major James H. Whitner.|
|Moved to Virginia and assigned to Evans’ Brigade.|
First Battle of Manassas (Bull Run)
The regiment lost 11 men killed, 79 wounded, and 6 men missing.
|April||In the army reorganization the 450 men of the regiment were consolidated into five companies and designated the 4th South Carolina Infantry Battalion. Colonel Sloan and Major Whittner were dropped and Lieutenant Colonel Charles S. Mattison was retained as major in command of the battalion.|