Data taken from the 1860 United States Census. Confederate cities are shaded.

Rank	City	State	Population
1	New York	New York	813,669
2	Philadelphia	Pennsylvania	565,529
3	Brooklyn	New York	266,661
4	Baltimore	Maryland	212,418
5	Boston	Massachusetts	177,840
6	New Orleans	Louisiana	168,675
7	Cincinatti	Ohio	161,044
8	St. Louis	Missouri	160,773
9	Chicago	Illinois	112,172
10	Buffalo	New York	81,129
11	Newark	New Jersey	71,941
12	Louisville	Kentucky	68,033
13	Albany	New York	62,367
14	Washington	District of Columbia	61,122
15	San Francisco	California	56,802
16	Providence	Rhode Island	50,666
17	Pittsburg	Pennsylvania	49,221
18	Rochester	New York	48,204
19	Detroit	Michigan	45,619
20	Milwaukee	Wisconsin	45,246
21	Cleveland	Ohio	43,417
22	Charleston	South Carolina	40,522
23	New Haven	Connecticut	39,267
24	Troy	New York	39,235
25	Richmond	Virginia	37,910
26	Lowell	Massachusetts	36,827
27	Mobile	Alabama	29,258
28	Jersey City	New Jersey	29,226
29	Allegheny	Pennsylvania	28,702
30	Syracuse	New York	28,119
31	Hartford	Connecticut	26,917
32	Portland	Maine	26,341
33	Cambridge	Massachusetts	26,060
34	Roxbury	Massachusetts	25,137
35	Charlestown	Massachusetts	25,065
36	Worchester	Massachusetts	24,960
37	Reading	Pennsylvania	23,162
38	Memphis	Tennessee	22,623
39	Utica	New York	22,529
40	New Bedford	Massachusetts	22,300
41	Savannah	Georgia	22,292
42	Salem	Massachusetts	22,252
43	Wilmington	Delaware	21,258
44	Manchester	New Hampshire	20,107
45	Dayton	Ohio	20,081
46	Patterson	New Jersey	19,586
47	Lynn	Massachusetts	19,083
48	Indianapolis	Indiana	18,611
49	Columbus	Ohio	18,554
50	Petersburg	Virginia	18,266