The 199th Pennsylvania Infantry lost 2 officers and 30 enlisted men killed or mortally wounded and 52 enlisted men to disease during the Civil War.

1864
September and October Organized at Philadelphia under Colonel James C. Briscoe, Lt. Colonel Ambrose A. Lechler and Major William A. F. Gehr
October Moved to Deep Bottom Landing, Va. Duty in trenches before Richmond, Va. attached to 1st Brigade, 1st Division, 10th Army Corps, Army of the James
October 22 Lt. Colonel Letcher discharged
November 28 Captain Robert P. Hughes of Company C promoted to lieutenant colonel
December Attached to 1st Brigade, 1st Division, 24th Army Corps
1865
March 28-April 9 Appomattox Campaign
April 2 Assaults on Forts Gregg and Alexander and Fall of Petersburg
April 3-9 Pursuit of Lee
April 6 Rice’s Station
April 9 Appomattox Court House. Surrender of Lee and his army.
April – May Duty at Richmond, Va.
June 28 Consolidated with 188th Pennsylvania Infantry under Colonel Briscoe