The 175th Pennsylvania Infantry Regiment lost 21 enlisted men to disease during the Civil War.

1862
November 6 Organized at Philadelphia under Colonel Samuel A. Dyer, Lt. Colonel Francis C. Hooten and Major Isaac McClure
December 1 Moved to Washington, D.C., then to Fortress Monroe and Suffolk, Va.
December Duty at Suffolk, Va. attached to Gibb’s’ Brigade, Division at Suffolk, Va., then Spinola’s Brigade, Division at Suffolk, 7th Corps
December 28-January 1 Moved to New Berne, N. C., and attached to 1st Brigade, 5th Division, 18th Corps, Dept. of North Carolina
1863
February 24 Major McClure resigns. Captain Joseph D. Smith of Company A is promoted to major.
March 6-10 Expedition from New Berne to Trenton, Pollocksville, Young’s Cross Roads and Swansborough
April 4-6 Operations on the Pamlico
April 7-10 Expedition to relief of Little Washington
April 13-21 Expedition to Swift Creek Village
May Garrison duty at Little Washington attached to District of the Pamlico, Dept. of North Carolina
June Moved to Fortress Monroe, Va., thence to Harper’s Ferry, W. Va., and to Frederick, Md.
July Withdrawn to Frederick, then returned to Sandy Hook, where it was attached to Well’s Brigade, Harper’s Ferry, W. Va., 8th Corps, Middle Department and assisted in laying a pontoon bridge over the Potomac.
August 7 Mustered out in Philadelphia