The 28th Infantry Regiment lost 2 officers and 45 enlisted men killed or mortally wounded and 1 officer and 164 enlisted men to disease during the Civil War.

1863
December 24 – March 31 Organized at Indianapolis, Ind.
1864
April 24 Left Indianapolis, Ind., for Washington, D.C. then moved to Alexandria, Va,
May Duty at Alexandria, Va. attached to Defenses of Washington, D.C., 22nd Corps
June 2 Moved to White House, Va. Attached to Abercrombie’s Command.
June 21 Accompanied Gen. Sheridan’s Cavalry through Chickahominy Swamps to Prince George Court House, with several skirmishes.
July Siege operations against Petersburg and Richmond attached to 2nd Brigade, 4th Division, 9th Corps, Army of the Potomac
July 30 Mine Explosion, Petersburg
August 18-21 Weldon Railroad
September Attached to 2nd Brigade, 3rd Division, 9th Corps
September 29-30 Poplar Grove Church
October 1 Poplar Grove Church
October 27-28 Boydton Plank Road, Hatcher’s Run
November On Bermuda front and before Richmond
December Attached to 3rd Brigade, 2nd Division, 25th Corps
1865
April 3 Occupation of Richmond
April 6-May 12 At City Point, Va., and St. Mary’s, Md., in charge of prisoners. Attached to District of St. Mary’s, 22nd Corps
June 10 Moved to City Point, Va., then to Texas
July 1 Duty at Brazos Santiago and Corpus Christi, Texas attached to Dept. of Texas
November 8 Mustered out