The 10th United States Infantry Regiment lost 3 officers and 83 enlisted men killed or mortally wounded and 3 officers and 49 enlisted men to disease during the Civil War. The regiment is referenced on a War Department marker at Antietam and honored by a monument at Gettysburg.

1861
 15 April Colonel E. B. Alexander commanded Fort Laramie, Nebraska Territory
Lieutenant Colonel C. F. Smith commanded Fort Crittenden, Utah.
Captain E.R.S. Canby commanded Companies A and F at Socorro, New Mexico
Company C at Fort Wise, Colo.
Companies D and K at Fort Laramie, Neb.
Company H at Pinos Ranch near Santa Fe, N.M.
1862
January Companies B, E, G and I – Duty in Defenses of Washington, D.C. attached to Sykes’ Regular Infantry (Reserve) Brigade. Army Potomac
February Companies A, F & H concentrated at Fort Craig
February 21 Companies A, F & H – Battle of Valverde, N.M.
March Companies B, E, G and I – Moved to the Virginia Peninsula
April 5-May 4 Companies B, E, G and I – Siege of Yorktown, Va.
April 8 Companies A, F & H – Albuquerque
April 15 Companies A, F & H – Peralta
May Companies B, E, G & I attached to 2nd Brigade, 2nd Division, 5th Army Corps, Army Potomac
June Companies D and K moved to Fort Kearney and duty there
June 25-July 1 Seven days before Richmond (Companies B, E, G & I )
June 26 Battle of Mechanicsville (Companies B, E, G & I )
June 27 Gaines’ Mill (Companies B, E, G & I )
June 30 Turkey Bridge (Companies B, E, G & I )
July 1 Malvern Hill (Companies B, E, G & I )
July August At Harrison’s Landing (Companies B, E, G & I )
August 16-28 Movement to Fortress Monroe, thence to Centerville. (Companies B, E, G & I )
August 28-September 2 Pope’s Campaign in Northern Virginia (Companies B, E, G & I )
August 29 Battle of Groveton (Companies B, E, G & I )
August 30 Second Battle of Bull Run (Companies B, E, G & I )
September to November 7 Companies C, F & H march to Fort Leavenworth, Kan.
September 6-22 Maryland Campaign (Companies B, E, G & I )
September 16-17
Battle of Antietam

Companies E, G & I of the 10th were attached to the 2nd United States Infantry under Captain John S. Poland of the 2nd. Company E was commanded by First Lieutenant George S. Lauman, Company G by Captain Henry E. Maynadier and Company I by Second Lieutenant William L. Kellog.

From the marker on the Antietam battlefield:

About noon of the 17th, the Battalion of the Second and Tenth U.S. Infantry crossed the Antietam and moved to the support of the Horse Batteries on the left (south) side of the Boonsboro Pike. After the withdrawal of these Batteries, Poland deployed the entire Battalion as skirmishers and, under heavy fire of canister and musketry, advanced to this point (Sherrick’s Lane), his right resting on the Boonsboro Pike, his line extending to the left, along the lane fence, in the direction of Sherrick’s House, on the road to Burnside Bridge. In this position he engaged the skirmishers of Garnett’s Brigade, his right advancing some distance beyond the farm lane and driving the enemy’s cannoneers from their guns on Cemetery Hill.

While thus engaged the 17th Michigan and the skirmishers of Willcox’s Division came up and relieved the left of his line, and the First Battalion, 14th U.S. Infantry formed about 210 yards in rear of his right.

Poland assembled his skirmishers on the center, and the Battallion of the 14th U.S. Infantry threw forward skirmishers on the right of the line.

His ammunition being exhausted, Poland withdrew to the cover of the hill east of this tablet and at dusk recrossed the Antietam.

September 19-20 Shepherdstown Ford (Companies B, E, G & I )
October At Sharpsburg (Companies B, E, G & I )
October 29-November 19 Movement to Falmouth, Va. (Companies B, E, G & I )
November 7 Companies C, F & H leave Fort Leavenworth, Kan. for Washington, D.C.
November 24 Companies C, F & H arrive Washington, D.C.
November 28 Companies C, F & H join Regiment at Aquia Creek, Va.
December 12-15 Battle of Fredericksburg
1863
January 20-24 “Mud March”
April 7 Companies D and K left Fort Kearney
April 27-May 6 Chancellorsville Campaign
April 30 Companies D and K join Regiment near Chancellorsville, Va.
May 1-5
Battle of Chancellorsville
June 11-July 24 Gettysburg Campaign
July 1-3
Battle of Gettysburg

Captain William Clinton brought three companies (D, G & H) to the field.

From the monument on Houck Avenue at Gettysburg:

July 2 Arrived with the Brigade in the morning and took position on the right of the Twelfth Corps. Later moved to the left and at 6 p.m. the Brigade form ed line with left on north slope of Little Round Top the right extending into the woods. Advanced across Plum Run and to the crest of the rocky wooded hill in front near the Wheatfield and facing left occupied the stone wall on the edge of the woods. The Confederates having opened fire on the right flank and advanced through the Wheatfield in the rear the Brigade was withdrawn under a heavy infantry fire on both flanks and from the rear and shot and shell from the batteries and was formed in line on the right of Little Round Top.

July 3 Remained in same position.

Casualties: killed 1 officer and 15 men; wounded 5 officers and 27 men; missing 3 men

July 5-24 Pursuit of Lee
August 16-20 Moved to New York and attached to Dept. of the East
September 14 At Fort Hamilton, N.Y. Harbor
1864
April 23 – April 29 Moved to front and Joined 9th Army Corps at Bealeton Station, Va. Attached to 1st Brigade, 1st Division, 9th Army Corps, Army Potomac
May 4-June 12 Rapidan Campaign
May 5-7
Battle of the Wilderness
May 8-21
Spotsylvania Court House
May 10 Ny River
May 12 Assault on the Salient
May 22-26 North Anna River
May 26-28 On line of the Pamunkey
May 18-31 Totopotomoy
June 1-12
Cold Harbor
June 1-3 Bethesda Church
June 11 Transferred to 1st Brigade, 2nd Division, 5th Army Corps
June 16-18 First Assault on Petersburg
June 16 –
October 25
Siege of Petersburg
August 18-21 Weldon Railroad
September 29-October 2 Poplar Springs Church, Peeble’s Farm,
October 12 to 25 Attached to Provost Guard, 2nd Division, 5th Army Corps, Army of the Potomac
October 25-29 Moved to Fort Hamilton, N.Y. Harbor. Attached to Dept. of the East
April 23 Moved to the field and Joined Army Potomac, at Burkesville, Va., attached to Headquarters, Army of the Potomac
May 2-12 March to Washington, D.C.
May 23 Grand Review
June-October Duty at Washington, D.C.
October 20-27 Moved to St. Louis, Mo., then to St. Paul, Minn.