The 6th West Virginia Infantry Regiment lost 8 enlisted men killed and mortally wounded and 2 officers and 167 enlisted men by disease during the Civil War.

1861
August 13 to December 26 Organized at Grafton, Mannington, Cairo, Parkersburg and Wheeling, W. Va. Regiment organized for railroad guard duty and served on line of the Baltimore & Ohio Railroad by detachments, at various points west of Sleepy Hollow entire term. Attached to Railroad District, West Virginia.
1862
March Attached to Railroad District, Mountain Department
April 12 Raid from Fairmont to Valley River and Bootheville and Skirmish at Valley River (Company A)
June 7 Skirmish at Big Bend
July Attached to Railroad District, 8th Army Corps, Middle Department
August 31 Skirmish at Weston (2 Companies)
September 3 Skirmish at Weston (Detachment)
September Attached to Railroad District, West Virginia
September 28 Skirmish at Standing Stone
November 9 Capture of St. George (Company B)
December Attached to 3rd Brigade, 2nd Division, West Virginia
1863
January Attached to Clarksburg, W. Va., 8th Army Corps
March Attached to 6th Brigade, 1st Division, 8th Army Corps
April Attached to Kelly’s Command, Reserve Division, West Virginia
April 18 Skirmish at Johnstown (Detachment)
April 23 Skirmish at Rowlesburg
April 26 Rowlesburg and Portland and Oakland, Md. (1 Company)
April 29 Skirmish at Bridgeport (Detachment)
April 29 Fairmont (Detachment)
April 30 Bridgeport
June Attached to Wilkinson’s Brigade, Scammon’s Division, Dept. of West Virginia
August 26 Sutton (Companies G & I)
August 27 Ball’s Mills and on Elk River (Detachment)
October 13 Bulltown, Braxton County (Detachment)
May 3 Bulltown (Detachment)
July 4 South Branch Bridge (Detachment) and Patterson’s Creek Bridge (Detachment)
July 27 Back Creek Bridge (Detachment)
August 1 Cumberland, Md. (1 Company)
August 4 New Creek (2 Companies)
August 20 Bulltown (Detachment)
August 24 Sutton (Detachment)
August 27 Nutter Hill (Detachment)
November 28 New Creek (Detachment)
April Attached to 1st Brigade, 1st Infantry Division, West Virginia
June 10 Mustered out