The regiment was assigned to the Department of Georgia.

Siege of Yorktown

Assigned to G. B. Anderson’s Special Brigade, D.H. Hill’s Division, Department of Northern Virginia.

Battle of Williamsburg

Battle of Seven Pines

The regiment brought 392 men to the field and lost over 150 casualties when it broke the center of the Federal line. Captain Osgood Lee of Company I was killed. Lieutenants Riched Cobb of Company D, L.Q.C. McCrary of Company F, John C. Beeks of Company G and Wilkins J. Rains of Company K were wounded.

Seven Days Battles

Gaines’ Mill (First Cold Harbor)

The regiment lost 9 men killed and 76 wounded. Lieutenant John Bunyan Right of Company F was killed.

Malvern Hill

Lieutenant Wade Harper of Company H was wounded.

Battle of South Mountain

Held Turner’s Gap all day against heavy Federal assaults.

Battle of Sharpsburg (Antietam)

The regiment was commanded by Colonel Levi B. Smith until he was killed. Lieutenant Colonel Zachary took over the regiment until he was wounded. Captain William H. Rentfro of Company E then took command as senior captain. The regiment lost 15 men killed and 89 wounded (60% casualties) fighting in the Cornfield, the Bloody Lane. and near the Dunker Church. Captain John Beeks of Company G was mortally wounded.

After the battle Lieutenant Colonel Zachary was promoted to colonel and Major Stubbs was elected lieutenant colonel effective September 17, Captain Charles Dennis of Company C was elected major, and First Lieutenant Jmes Murray was elected captain of Company C.

From the War Department marker for Colquitt’s Brigade on the Antietam battlefield:

Colquitt’s Brigade formed line soon after sunrise, southwest of Mumma’s house, in support of Trimble and Ripley. It followed Ripley across the Smoketown Road and formed on his right.

After a severe engagement, involving heavy loss, it retired to the west end of the Bloody Lane and assisted in checking the advance of French’s Division of the Second Corps. Later in the day, portions of the Brigade acted with Evans’ Brigade in checking the Federal advance on the Boonsboro Pike.

From the War Department marker for Colquitt’s and Garland’s Brigades on the Antietam battlefield:

After the repulse of the Confederate line in the East Woods and Cornfield north of the Smoketown Road in the morning of the 17th, parts of the Brigades of Colquitt and Garland rallied in the Sunken Road at this point, their right connecting with Rodes, their left resting on the Hagerstown Pike. They cooperated with Rodes in repelling the advance of French’s Division, Second Corps, and, in cooperation with detachments of McLaws’ and Walker’s Division, crossed this road and attacked the right flank of French’s Division but were repulsed. In the afternoon, parts of the two Brigades were collected at Sharpsburg and moved out on the Boonsboro Pike in support of Evans’ Brigade in its resistance to the advance of a portion of the Fifth Army Corps.

Battle of Fredericksburg

The regiment was on the extreme right of the Federal line and only lightly engaged.

Battle of Chancellorsville

The regiment took part in Jackson’s flank attack, losing 31 casualties.

Charleston Harbor

Moved to Charleston, South Carolina and assigned to 1st Sub-Division, 1st Military District of South Carolina, Department of South Carolina, Georgia and Florida.
Company B assigned to 4th Sub-Division, 1st Military District of South Carolina, Department of South Carolina, Georgia and Florida.

Battle of Olustee

The regiment lost 7 men killed and 67 wounded. Lieutenant Wade Harper of Company H was wounded in the left knee.

Drewry’s Bluff

Battle of Cold Harbor

Siege of Petersburg

Captain Robert Patton of Company A was captured. Lieutenant Robert C. Evans of Company H died.

The Crater

Fort Harrison

Second Battle of Fort Fisher

Carolinas Campaign

Battle of Bentonville

Major William Rentfro was mortally wounded. Lieutenant Riched Cobb of Company D was wounded in the arm.

Durham Station

Surrendered with Johnston’s army under the command of Colonel Zachary.